Clinical worsening (CW) is a composite end point commonly used in pulmonary arterial hypertension (PAH) trials. We aimed to assess the trial-level surrogacy of CW for mortality in PAH trials, and ...

The Canadian Community Health Survey (CCHS) consists of two cross-sectional surveys conducted over a two-year repeating cycle. The first survey (2001, 2003, 2005, etc.) collects data from over 130,000 ...

Sunflower (Helianthus annuus L.) is an allogamic plant, which needs insects on flowering, especially the honeybees for seed production. Collecting nectar and pollen by honeybees in agricultural crops ...

aDepartment of Orthopaedics, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China bXiangya School of Medicine, Central South University, Changsha, 410008, Hunan, China ...

Tau pathology is a core driver of neurodegeneration in Alzheimer’s disease. Although numerous tau-targeting therapies have been developed, their overall efficacy and safety remain unclear, because of ...

This open access article is distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) license. This work is licensed under a Creative Commons ...

The Xbox Series X and S had no small task in trying to compete with the best PS5 games and the best Switch games at the same time. While it did get off to a slow start for the generation, its library ...

Olaparib as Treatment Versus Nonplatinum Chemotherapy in Patients With Platinum-Sensitive Relapsed Ovarian Cancer: Phase III SOLO3 Study Final Overall Survival Results We conducted a prospective ...

5 Division of General Internal Medicine and Health Services Research, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA 6 Department of Health Policy and Management, UCLA Fielding School ...

Broccoli head rot, also known as pin rot, can cause significant problems, especially in fall broccoli production in Salinas Valley. Two types of head rot are affecting broccoli, including bacterial ...