B-cell depletion therapies, in which B cells of the immune system that may drive disease activity in multiple sclerosis (MS) ...

Cells manage a wide range of functions in their tiny package — growing, moving, housekeeping, and so on — and most of those functions require energy. But how do cells get this energy in the first ...

The 2020 Nobel Prize in Chemistry was awarded for the development of CRISPR/Cas9, a method also known as "gene scissors," which enables researchers to better understand how human cells function and ...

Cells can spontaneously change shape even without external signals, but the underlying mechanisms behind this form of self-organization have remained unclear. Now, researchers from Japan have ...

Immune aging weakens protective responses against infection, cancer, and poor tissue repair, while increasing chronic inflammation and autoimmune risk. Domains of immune aging. With advancing age, ...

Scientists at City of Hope have uncovered a gene called SMOC1 that plays a surprising role in the development of type 2 diabetes (T2D) by converting pancreatic cells that normally produce insulin into ...

A new review argues that aging may not be just a collection of molecular defects, but a progressive drift in cell identity that links inflammation, fibrosis, mitochondrial damage, and tissue decline.

Until now, doctors knew hepatic stellate cells mainly as drivers of liver fibrosis. The actual functions of this cell type have hardly been studied to date. Researchers have now determined that ...

Crypt-base-columnar cells are continuously dividing intestinal stem cells that generate IECs, which are composed by distinct specialised cell types that play different functions: Enterocytes (in the ...